Indirectly. By copying a data.bin from a cleared save file and replacing your current one, you can jump directly to NG+. But you will lose chapter progress.
Here is the gold standard for manual backup. save data resident evil 4 remake pc
C:\Program Files (x86)\Steam\userdata\[Your Steam ID]\2050650\remote\win64_save Indirectly
C:\Users\[YOUR_USERNAME]\AppData\Local\ Capcom\Resident Evil 4 Demo\ (For Demo) C:\Users\[YOUR_USERNAME]\AppData\Local\Capcom\ResidentEvil4\ (For Full Game) save data resident evil 4 remake pc